Will GLP-1s help or hurt your sex life? The research is nuanced — but for most men, the news is good. Better erections, improved libido, and preserved fertility.
A Ljubljana study (2024) found that semaglutide improved sperm morphology from 2% to 4% normal forms (p=0.012), while TRT significantly decreased sperm concentration and total count. For men planning families, GLP-1s may be the better choice for weight loss — they improve fertility markers instead of suppressing them.
Sexual function is complex. Obesity causes ED through inflammation, vascular damage, and hormonal disruption. Losing weight reverses these — which is why most men report improved sexual function on GLP-1s despite the appetite suppression.
Evidence-based coverage of erectile function, libido, fertility, and dating on GLP-1 medications.
Can weight loss drugs improve ED? The mechanisms and evidence.
⚡ ResearchLjubljana study shows GLP-1s improved sperm while TRT destroyed it.
GuideThe conflicting reports explained — and what predicts your outcome.
⚡ ResearchTirzepatide outperformed testosterone replacement for erectile dysfunction.
Lifestyle3X more confidence, 2X more matches — but stigma remains.
GuideWhat to know if you're trying to conceive — and how timing matters.
Compare GLP-1 telehealth providers — some also offer ED medications if needed.